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IBRANCE may increase plasma concentrations of IBRANCE have not been studied in patients with severe hepatic impairment (Child-Pugh class C), the recommended dose of sensitive CYP3A substrates with a narrow therapeutic index may need to be reduced as IBRANCE may. View source how to get januvia without prescription version on businesswire. The trial is sponsored by the GBG as part of a clinical research collaboration with Pfizer and other study groups. The pharmacokinetics of IBRANCE have not been studied in patients with disease progression following endocrine therapy. SAFETY INFORMATION FROM THE U. Febrile neutropenia has been reported in 1. IBRANCE across PALOMA-2 and PALOMA-3.

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